MRI对CT不逊于第1阶段睾丸睾丸研讨会。在6年期间,无论成像模态如何,3次扫描计划都不为7扫描计划。使用MRI而不是CT可以减少该患者群体中的辐射暴露[1]。目前的指导方针倡导1阶段睾丸癌患者睾丸切除术后CT监测。虽然这种癌症的存活率高,但由于CT扫描,虽然反复暴露于辐射产生的长期不利健康效果。第3阶段TRISST试验(nct00589537.)试图证明减少的CT调度或MRI的不逊色,以安全有效地监测1阶段睾丸癌的患者。调查人员将669名男性随机化为4个臂中的1个,其中2个用CT监测,其中2个用MRI监测其中2个。每个成像模型ARM有2个不同的频率时间表:一个扫描患者,6,12,18,24,36,48和60个月;其他扫描患者在6,18和36个月。所有患者均遵循6年。主要结果措施是与皇家马尔顿医院≥2C疾病复发的患者的比例。在669名试验参与者中,退缩了82(12%)。这些82中只有10个被评分为≥2C复发。在预定成像时诊断大部分复发;此外,超过3年的复发是罕见的。 Although there were more events in those who received 3 scans instead of 7, the criteria for non-inferiority were still met. Fewer events were observed in those who received MRI scans compared with CT. No tumor-related deaths occurred and the 5-year disease-free survival and overall survival rates were similar across all groups. Researchers asserted that surveillance is both safe and effective in stage 1 testicular seminoma, regardless of frequency or type of imaging. Furthermore, imaging beyond 3 years may actually be unnecessary, as relapse after 3 years is rare. Finally, they recommend that the standard of care should recommend MRI instead of CT, in an attempt to limit radiation exposure in this young population.
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  1. Joffe J. Imaging Is Seaginoma睾丸癌监测中的成像和频率:随机,III,阶段,因子试验(TRISST)的结果。asco Geatitureariarariase癌症研讨会,2011年2月11日至13日。