新型冠状病毒病具有传播力强、临床表现多样、潜伏期长等特点。除了感染呼吸系统外,COVID-19还会对心血管系统产生不良影响。COVID-19会造成急性心肌损伤,也会对心血管系统造成慢性损害。
本综述旨在提供关于COVID-19和心血管系统的最新信息。检索PubMed、Scopus、Science direct和谷歌Scholar。
提示COVID-19感染引起的心脏损伤可能是患者出现严重临床表型或不良事件的重要原因。COVID-19患者的心肌损害与病情严重程度甚至预后密切相关。除COVID-19引起的心血管系统紊乱外,应加强对已有心血管疾病(CVD)患者的保护。因此,COVID-19患者一旦出现相关症状,必须迅速接受治疗,以降低死亡率。因此,建议在已有心血管疾病的患者因COVID-19感染住院后早期测量心脏损伤生物标志物,同时仔细监测可能由感染引起的任何心肌损伤。特护病房;2019新型冠状病毒;:血管紧张素转化酶抑制剂;:急性冠脉综合征;:急性呼吸窘迫综合征; : Ang II type 1 receptor; : Adenosine triphosphate; : American College of Cardiology; : Angiotensin converting enzyme; : Angiotensin II; : Angiotensin II receptor blocker; : Atrioventricular block; : Coronary artery disease; : Cardiovascular disease; : Computerized tomography; : Congestive heart failure; : Coronary heart disease; : Creatine kinase isoenzyme-MB; : C-reactive protein; : Cardiac troponin I; : Epicardial adipose tissue; : Extracorporeal membrane oxygenation; : Food and Drug Administration; : Granulocyte colony-stimulating factor; : HF with a reduced ejection fraction; : Human isoform of ACE2; : Interleukin; : Intra-aortic balloon counterpulsation; : Interferon γ-induced protein 10 kDa; : Lysophosphatidylcholine; : Mitochondrial assembly receptor; : Monocyte chemoattractant protein-1; : Middle East respiratory syndrome; : macrophage inflammatory protein 1a: : Multiple organ failure; : Myocardial infarction; : Magnetic resonance imaging; : Myohe-moglobin; : N-terminal pro-brain natriuretic peptide; : Percutaneous cardiopulmonary assistance; : Recombinant human ACE2; : Severe acute respiratory syndrome; : T helper; : Renin-angiotensin system; : Tumor necrosis factor-α; : World Health Organization.

参考

PubMed.