研究内镜鼻窦外科(ESS)后可吸收止血粉的疗效和患者舒适性。共有21岁(17名男性,4名女性)患者,平均年龄为42岁(从18至65岁),在2015年10月至2019年10月之间的首都医科大学北京宁戈伦医院慢性鼻窦炎(CRS)的双侧ESES进行了纳入使用内腔控制设计比较吸收止血粉与鼻孔的影响。随机对照试验在同一患者的左侧和右鼻腔中进行。如果在实验鼻腔中施加止血粉末,则鼻孔被施用于对照鼻腔。平均术前窦房位断层扫描(CT)得分为6.25。所有患者均使用视觉模拟规模(VAS,10分)在基线,通过1,7,14和30天使用症状日记。包括出血,面部疼痛,鼻塞,使用VAS的鼻排放,双方都记录了两侧的结果。还研究了术后内窥镜评分。SPSS 22和GraphPad Prism 8.0统计软件用于分析。 Paired -test or nonparametric test was used between the test side and the control side. The difference was statistically significant (0.05). The bleeding score and total nasal symptom VAS scores at postoperative days (POD) 1, 7, 14 and 30 were not significantly different(1.341, 0.552, 0.631, 0.158, all 0.05;0.944, 1.471, 1.612, 2.251, all 0.05). There was no significant difference between absorbable hemostasis powder and Nasopore side on POD 1, 7, 14 and 30 in terms of each nasal symptom VAS scores(all 0.05). On POD 1, 7 and 14, the packing material degeneration scores of the absorbable hemostasis powder side were significantly lower than those of the Nasopore side [(1.33±0.21)(2.00±0.00),(0.38±0.18) (1.95±0.22), 0 (1.80±0.13), all 0.01]. There were significant differences between absorbable hemostasis powder and Nasopore side on POD 1, 7, 14 and 30 in terms of endoscopic scores (edema, crusting, discharges, scar, polyps and material degeneration, 3.07, 7.00, 6.41, 2.69, all 0.05). The absorbable hemostasis powder and Nasopore has similar postoperative hemostasis effect. The absorbable hemostasis powder is rapidly cleared and without negative effects on mucosal wound healing 14 days postoperatively.

参考

PubMed.